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Facial Aesthetics

There are two particularly important substances — collagen and hyaluronic acid — that play important roles in keeping facial skin looking smooth and supple. Collagen is a protein that provides skin with structural support, while hyaluronic acid is a natural sugar found in all living cells that attracts and binds water, hydrating the skin and giving it volume.

As the skin ages and is exposed to environmental pollutants and ultraviolet rays, collagen and hyaluronic acid in the skin diminish, the skin loses structure and volume, and unwelcome lines and wrinkles appear, like those "parentheses" lines around your nose and mouth.

Other lines, like glabellar lines (the vertical frown lines between the eyebrows which often look like the number "11"), are formed by repeated and involuntary contraction of the muscles between the eyebrows. As the skin becomes less elastic, excessive contraction of these muscles may cause visible, deep wrinkles between the eyebrows to form, even when the face is relaxed.

As a world leader in medical aesthetics, Allergan is deeply committed to the Science of Rejuvenation™ — that is, to developing and delivering high quality, science-based aesthetic solutions and experiences. Allergan is the only company with a global facial aesthetics franchise offering aesthetic specialty physicians and their patients the most comprehensive array of innovative aesthetic products. Allergan's Total Facial Rejuvenation™ portfolio is where science and aesthetics meet. The portfolio includes BOTOX® Cosmetic (onabotulinumtoxinA), an injectible to temporarily reduce the appearance of moderate to severe glabellar lines - the vertical frown lines between the eyebrows that look like an "11" - in adult women and men aged 18 to 65, and hyaluronic acid dermal fillers including the JUVÉDERM® dermal filler gel family of products, the first and only hyaluronic acid dermal fillers clinically proven to last for up to one year. It also includes advanced, anti-aging physician-dispensed products such as VIVITÉ®, M.D. FORTÉ® and PREVAGE® MD, which contains idebenone, the most powerful antioxidant available in a skin care product today.

Important Information about JUVÉDERM®  


BOTOX® Cosmetic (onabotulinumtoxinA) Important Information


Approved Uses

BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of both moderate to severe crow’s feet lines and frown lines between the eyebrows in adults.

IMPORTANT SAFETY INFORMATION
BOTOX® Cosmetic may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic:

  • Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several month
  • Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing. If this happens, do not drive a car, operate machinery, or do other dangerous activities

The dose of BOTOX® Cosmetic is not the same as, or comparable to, any other botulinum toxin product.

There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines, crow's feet lines or both at the same time.

Serious and/or immediate allergic reactions have been reported. They include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.

Do not take BOTOX® Cosmetic if you: are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.

Tell your doctor about all your muscle or nerve conditions, such as amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX® Cosmetic.

Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; weakness of forehead muscles, such as trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to breast-feed (it is not known if BOTOX® Cosmetic passes into breast milk).

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal products. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past.

Especially tell your doctor if you: have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin, such as Myobloc®, Dysport®, or Xeomin® in the past (be sure your doctor knows exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners.

Other side effects of BOTOX® Cosmetic include: dry mouth, discomfort or pain at the injection site, tiredness, headache, neck pain, and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids, swelling of your eyelids, and dry eyes.

For more information refer to the Medication Guide or talk with your doctor.

To report a side effect, please call Allergan at 1-800-433-8871.

Please see BOTOX® Cosmetic full Product Information including Boxed Warning and Medication Guide.

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